Delivering a First-to-Market Thermocycler with Real-Time DNA Amplification and Sequencing for Genetic Analysis
A genomics technology company had a concept for a novel real-time thermocycler that they wanted to bring to market. This special thermocycler would offer 96 individually controlled wells for greater flexibility and precision in DNA amplification and sequencing. Ascential provided full-scale development and contract manufacturing support, helping reduce development time while enabling a first-to-market platform […]
Developing a Scalable Next-Generation Sequencer with Proprietary Chemistry
Integrating Complex Subsystems for Class II IVD Compliance A leading life sciences company needed a fully automated, high-precision sequencing system capable of handling sensitive reagents, managing complex multi-channel fluidics, and integrating third-party components for efficient sequencing based on proprietary chemistry. The system had to support strict regulatory compliance for Class II IVD and IEC 61010 […]
Transforming a Manual Lab Process into a High-Volume, Precision Manufacturing System
Oligo Synthesis System: Factory Floor Automation for DNA Strand Production A medical device company needed to automate manual lab processes for producing unique DNA calibration strands used in sequencing equipment. The program required a full journey from concept and prototyping through hardware, software, user interface design, supply chain development, verification testing, manufacturing, and after-market support. […]
Automating Liquid-Based Cytology Sample Preparation at Diagnostic Scale
From Manual Workflows to Fully Integrated Pre-Analytical Automation A global diagnostics company sought to eliminate manual, error-prone sample preparation from its liquid-based cytology workflow for STI and HPV testing without compromising throughput, accuracy, or laboratory compatibility. Ascential delivered a 144-sample automated benchtop platform with real-time sample control and seamless integration into existing molecular diagnostics infrastructure. […]
Engineering an Automated Platform for High-Throughput Multiplex Proteomics
A fast-growing biotechnology company sought to commercialize an advanced proteomic analysis platform capable of delivering precise, multiplexed data through a streamlined sample-to-data workflow. The company needed a development partner that could rapidly engineer a functional prototype, integrate highly complex subsystems into a compact architecture, and position the platform for scalable manufacturing. Ascential engineered and refined […]
Sustaining a High-Throughput Genomic Analysis Platform for Long-Term Market Success
From Concept to FDA Breakthrough A precision diagnostics client sought to dramatically reduce the time required to identify effective antibiotics for critically ill patients — without sacrificing accuracy or throughput. Ascential delivered a three-instrument automated system that achieved FDA Breakthrough Device Designation. Faster reagent dispensing across the full testing workflow 0 x Increase in throughput, […]
Transforming a Proof-of-Concept Optofluidic Platform into a Commercial-Grade Instrument
From Concept to FDA Breakthrough A precision diagnostics client sought to dramatically reduce the time required to identify effective antibiotics for critically ill patients — without sacrificing accuracy or throughput. Ascential delivered a three-instrument automated system that achieved FDA Breakthrough Device Designation. Faster reagent dispensing across the full testing workflow 0 x Increase in throughput, […]
Delivering a Next-Generation Automated Sample Preparation and Imaging System
From Concept to FDA Breakthrough A precision diagnostics client sought to dramatically reduce the time required to identify effective antibiotics for critically ill patients — without sacrificing accuracy or throughput. Ascential delivered a three-instrument automated system that achieved FDA Breakthrough Device Designation. Faster reagent dispensing across the full testing workflow 0 x Increase in throughput, […]
Automating Oligonucleotide Synthesis for Scalable, Standardized Production
From Concept to FDA Breakthrough A precision diagnostics client sought to dramatically reduce the time required to identify effective antibiotics for critically ill patients — without sacrificing accuracy or throughput. Ascential delivered a three-instrument automated system that achieved FDA Breakthrough Device Designation. Faster reagent dispensing across the full testing workflow 0 x Increase in throughput, […]
Standard Catheter Steps Ripe for Automation eBook
